Job Description

Laboratory Manager - Lessard Lab
Department: Genes & Human Disease
Location: Oklahoma City, OK
Position Overview and Responsibilities
The Lessard Lab is seeking a Laboratory Manager to perform advanced cell and molecular biology techniques including, but not limited to, in vitro cell culture (mammalian cells, primary cells, and human inducible pluripotent stem cells (hiPSCs)), CRISPR genome editing, and single cell sequencing and spatial transcriptomics technologies (i.e., latest 10X Genomics platforms).
The Laboratory Manager is responsible for the following:

Supervises laboratory personnel according to policies and procedures and applicable laws. Manages lab operation to include completion of specific projects by providing input within area of expertise.

Modifies, develops, maintains and improves lab procedures and/or protocols.

Identifies, prepares and performs a limited number of specialized, complex research experiments, develops protocols to enhance procedures, analyzes data and presents results to Principal Investigator.

Assists with preparation of research results for publications, grants, and presentations.

Coaches and provides technical advice to employees/affiliates involved in a project within the lab.

Operates highly specialized equipment requiring a high degree of skill.

Acts as a technical resource for the laboratory. Develops solutions to technical problems of extensive scope and complexity within area of expertise.

Builds constructive relationships with other labs and technical advisers to assist with experimental design and procedures.

Orders lab supplies and equipment.

Maintains lab notebook in an appropriate manner of all tasks performed. Ensures all other employees in the lab do as well.

Enhances own knowledge by learning new techniques and keeping current with emerging technologies, equipment, and protocols.

May perform literature searches.

Addresses complaints and works with supervisor and Human Resources to resolve employee issues.

Maintains a safe and clean work environment in compliance with safety procedures and according to federal regulations.

Performs other duties as assigned by supervisor.
Minimum Qualifications
BS/BA/MS degree in one of the biological sciences, chemistry, physics or related area and a minimum of ten (10) years relevant research experience. A minimum of four (4) years supervisory experience required.
Highly skilled in multi-tasking, thinking, working independently, and functioning effectively as a team member.
Develops constructive and cooperative working relationships with vendors, co-workers, scientific and administrative staff and maintain them over time.
Demonstrates a high level of expertise in specific scientific field. Performs a broad range of assignments with a high level of accuracy, thoroughness, and effectiveness. Careful with details and thorough in completing work tasks and reports. Capable of handling more complex projects, assignments, and assuming greater responsibly.
Takes the initiative in developing new methods, procedures, and approaches to lab procedures and protocols.
Makes frequent and valuable suggestions to improve the efficiency of the lab to the supervisor.
Excels in organizing, interpreting, and communicating project data effectively with coworkers, technical advisors, collaborators, and supervisor. Composes, reads, and comprehends complex instructions, correspondences and protocols/procedures, including performing complex mathematical computations and writing complex reports and correspondence. Excels in the navigating the Internet for essential information and using computers to generate meaningful information and increase efficiency.
Displays leadership traits appropriate to the situation. Excels in training, leading, and motivating subordinates. Assists subordinates in applying new skills, techniques, and understandings. Responds quickly to new instructions, situations, methods, and procedures, and shares learning experience with subordinates.
Successfully prioritizes when faced with requests, demands, and deadlines. Performs effectively despite sudden deadlines and changing priorities. Keeps calm and professional under stressful situations. Excels in anticipating approaching problems and opportunities. Displays a commitment to high ethical standards.
Preferred Qualifications
Ph.D. in one of the biological sciences, chemistry, physics or related area.
Ten (10) years of hands-on experience using 10X Genomics Single Cell Technologies (scFLEX/scFFPE, 5'CITEseq, Xenium, etc.) and other high-throughput sequencing approaches (ATAC-seq, RNA-seq, SMART-seq, Perturb-seq, HiC, etc). Hands-on experience with sample and library preparation for Illumina sequencing platforms. Experience culturing and differentiating human inducible pluripotent stem cells, performing CRISPR Cas9-targeted editing, flow cytometry, molecular cloning, database development and/or management, experience working with human tissues, and previous experience managing a lab of >15 staff are also preferred.
OMRF Overview
Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation's oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer's disease, cancer, lupus, multiple sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation's leaders in patents per scientist.
Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a collective commitment to our mission, ". . . so that more may live longer, healthier lives." Successful candidates will demonstrate commitment to this mission.
OMRF Benefits:
We offer competitive salaries and comprehensive benefits to full-time employees including medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, and paid holidays. All employees have access to our onsite cafe, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro. Learn more about our benefits here.
OMRF is an Equal Opportunity Employer.
To apply, visit https://omrf.hrmdirect.com/employment/job-opening.php?req=3463231&req_loc=915425&&#job

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